Which of the following is a sign of poor perfusion?

Weak pulses are indeed a sign of poor perfusion. When the body's tissues are not receiving an adequate blood supply, the heart may struggle to maintain sufficient pressure to generate strong pulses. This can occur in various situations, including severe dehydration, shock, or heart failure.

In contrast, high blood pressure typically indicates good perfusion, as it suggests that the heart is effectively pumping blood with enough force. Bright red skin is often a sign of adequate blood flow and can suggest increased circulation to the skin, rather than impaired perfusion. A decreased heart rate may also reflect improved perfusion, especially in certain contexts; it can happen when the body is resting or in a well-perfused state. Therefore, weak pulses serve as a more direct indicator of compromised blood circulation and tissue perfusion.